A method for producing a hop extract, comprising a step of filtering hop-containing water at 50 ° C. or higher to obtain a hop extract. The production method of the present invention is capable of easily preparing a hop extract with a high polyphenol concentration, neutralizing protein toxins, suppressing enamel demineralization, body fat adjustment, periodontal ligament protection, virus inactivation, thymic Raw material of composition for treatment and / or improvement of overexpression suppression of interstitial lymphocyte formation factor, symbiotic regeneration, anti-inflammatory, inflammatory bowel disease, coronary artery disease, obesity, hyperuricemia, allergic disease, digestive system disease, etc. Is preferably used.50℃以上のホップ含有水をろ過して、ホップ抽出液を得る工程を含む、ホップ抽出液の製造方法。本発明の製造方法は、ポリフェノール濃度が高いホップ抽出液を簡便に調製することできるものであり、蛋白質毒素中和、エナメル質脱灰抑制、体脂肪調整、歯根膜保護、ウィルス不活化、胸腺間質性リンパ球新生因子過剰発現抑制、共生再生、抗炎症、炎症性腸疾患、冠動脈疾患、肥満症、高尿酸血症、アレルギー疾患、消化器疾患等の治療及び／又は改善用組成物の原材料として好適に用いられる。
