Kenneth Allan Brasel,James F Smothers,Douglas Pat Cerretti
申请号：
US13967037
公开号：
US09303084B2
申请日:
2013.08.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-1, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.
