Kenneth Allan BRASEL;Jilin SUN;Stephen FOSTER;James F. SMOTHERS;Christopher MEHLIN;Douglas Pat CERRETTI
发明人:
Kenneth Allan BRASEL,James F. SMOTHERS,Douglas Pat CERRETTI,Christopher MEHLIN,Jilin SUN,Stephen FOSTER
申请号：
US13466850
公开号：
US20120230987A1
申请日:
2012.05.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-1, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.
