BRASEL, Kenneth, Allan,FOSTER, Stephen,CERRETTI, Douglas, Pat,SUN, Jilin,SMOTHERS, James, F.,MEHLIN, Christopher
申请号:
DK08798203
公开号:
DK2188313T3
申请日:
2008.08.19
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-I, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.