Paul B. Fisher,Swadesh K. Das,Rupesh Dash,Devanand Sarkar,Siddik Sarkar,Jolene Windle
申请号：
US14895247
公开号：
US09750823B2
申请日:
2014.06.04
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Recombinant vectors in which expression of one or more elements (e.g. genes required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by a truncated CCN 1 cancer selective promoter (tCCN1-Prom) are provided, as are cells and transgenic animals that contain such vectors. The vectors are used in cancer therapy and/or diagnostics, and the transgenic mice are used to monitor cancer progression, e.g. in screening assays.
