USE OF A TRUNCATED CCN1 PROMOTER FOR CANCER DIAGNOSTICS, THERAPEUTICS AND THERANOSTICS

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专利权人:

VIRGINIA COMMONWEALTH UNIVERSITY

发明人:

FISHER, PAUL, B.,DAS, SWADESH, K.,DASH, RUPESH,SARKAR, DEVANAND,SARKAR, SIDDIK,WINDLE, JOLENE

申请号：

EP14817622

公开号：

EP3003022A4

申请日:

2014.06.04

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Recombinant vectors in which expression of one or more elements (e.g. genes required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by a truncated CCN 1 cancer selective promoter (tCCN1-Prom) are provided, as are cells and transgenic animals that contain such vectors. The vectors are used in cancer therapy and/or diagnostics, and the transgenic mice are used to monitor cancer progression, e.g. in screening assays.

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中国工程科技知识中心

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