BISCHOFF, FRANCOIS PAUL,VELTER, ADRIANA INGRID,ROMBOUTS, FREDERIK JAN RITA,DE CLEYN, MICHEL ANNA JOZEF,VAN BRANDT, SVEN FRANCISCUS ANNA,GIJSEN, HENRICUS JACOBUS MARIA,ZAVATTARO, CHIARA,VAN DEN KEYBUS,
申请号：
CA2891755
公开号：
CA2891755A1
申请日:
2014.01.16
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention is concerned with novel substituted pyrido-piperazinone derivatives of Formula (I) wherein R1, R2, R3, R4, R5, L, Z and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
