MINNE, GARRETT BERLOND,BISCHOFF, FRANCOIS PAUL,GIJSEN, HENRICUS JACOBUS MARIA,VELTER, ADRIANA INGRID,PIETERS, SERGE MARIA ALOYSIUS,BERTHELOT, DIDIER JEAN-CLAUDE
申请号:
CA2841102
公开号:
CA2841102C
申请日:
2012.07.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention is concerned with novel substituted indole derivatives of Formula (I) wherein R1, R2, R3, A1, A2, A3, Y and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.