Andreas Faust,Sven Hermann,Johannes Roth,Michael Schaefers,Thomas Vogl
申请号：
US15522536
公开号：
US20170333577A1
申请日:
2015.10.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present application provides quinoline-3-carboxamide compounds covalently linked to a label for use in the diagnosis of an inflammatory disease at local site. The above mentioned compounds can be used to detect or image accumulation of S100A9 in the body of a subject at sites of inflammation, using in vivo non-invasive molecular imaging techniques for the detection of said compounds. Accordingly, labeled quinoline-3-carboxamide compounds can be applied to evaluate the risk of a subject of developing an inflammatory disease and to follow the progress of the disease.
