Javier Cote-Sierra,Antonio Iglesias,Claas Aiko Meyer
申请号：
US14476626
公开号：
US20150026832A1
申请日:
2014.09.03
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.
