Javier Cote-Sierra,Antonio Iglesias,Claas Aiko Meyer
申请号：
US13867263
公开号：
US20130318641A1
申请日:
2013.04.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.
