Song Li,Wu Zhong,Zhibing Zheng,Junhai Xiao,Bing Li,Yunde Xie,Xinbo Zhou
申请号:
US13263790
公开号:
US09149467B2
申请日:
2010.03.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a sustained-release composition containing 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole or a pharmaceutically acceptable salt thereof as an active ingredient, preparation thereof and the compound. The composition is suitable for oral administration by one time per day, and achieves the peak plasma concentration at 1.0 to 3 hours after oral administration. The composition is suitable for manufacturing a medicament for treatment of cognitive dysfunction syndrome, Alzheimers disease, Parkinsons disease, Huntingtons disease, or senile dementia.