Gary Cupit,Anne McCormick,Mary Osbakken,Christine Blumhardt
申请号：
US13139881
公开号：
US20120039954A1
申请日:
2009.12.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method of treating insomnia comprising administering to a subject a formulation including zaleplon, wherein the formulation is adapted to release the zaleplon after a lag time of at least about one hour after administration of the formulation, and during which substantially no drug substance is released provide a time of peak plasma concentration of about 3 hours to about 6 hours after administration provide an elimination half-life after the time of peak plasma concentration of about 0.5 hours to about 0.3 hours and provide an area under the curve of about 70 ng·h/mL to about 90 ng·h/mL.
