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MÉTHODE DE TRAITEMENT DES INSOMNIES
专利权人:
INC.;SOMNUS THERAPEUTICS
发明人:
CUPIT, GARY,MCCORMICK, ANNE,OSBAKKEN, MARY,BLUMHARDT, CHRISTINE
申请号:
EP09835582
公开号:
EP2375903A4
申请日:
2009.12.15
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A method of treating insomnia comprising administering to a subject a formulation including zaleplon, wherein the formulation is adapted to release the zaleplon after a lag time of at least about one hour after administration of the formulation, and during which substantially no drug substance is released; provide a time of peak plasma concentration of about 3 hours to about 6 hours after administration; provide an elimination half-life after the time of peak plasma concentration of about 0.5 hours to about 0.3 hours; and provide an area under the curve of about 70 ng·h/mL to about 90 ng·h/mL.
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