Allan Zijian ZHAO,Sijia GONG,Yan LIN,Fanghong LI,Xiaoxi LI
申请号：
US16075145
公开号：
US20180369188A1
申请日:
2017.03.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention discloses uses of a novel phosphodiesterase 4 (PDE4) inhibitor ZL-n-91 in preparing drugs against lung cancer proliferation and metastasis. The mouse survival curves and in vitro cell experiments show that the PDE4 inhibitor ZL-n-91 can significantly inhibit the proliferation and metastasis of lung cancer cells, indicating that this PDE4 inhibitor ZL-n-91 can become an important target for the studies on anti-lung cancer proliferation and metastasis, to provide a basis for preparing drugs against lung cancer proliferation and metastasis, with promising prospect of development and application.
