Thomas LINKE,William K. WANG,Ambarish SHAH,Hasige SATHISH,Alan HUNTER,Christopher THOMPSON
申请号：
US16124441
公开号：
US20180371094A1
申请日:
2018.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.
