LINKE, THOMAS,WANG, WILLIAM, K.,SHAH, AMBARISH,SATHISH, HASIGE,HUNTER, ALAN,THOMPSON, CHRISTOPHER
申请号：
EP11813105
公开号：
EP2613857A4
申请日:
2011.07.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.
