Thomas Linke,William K. Wang,Ambarish Shah,Hasige Sathish,Alan Hunter,Christopher Thompson
申请号：
US15423928
公开号：
US10072083B2
申请日:
2017.02.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides methods for isolating an active polypeptide or immunoconjugate by purification of a solution containing both the active polypeptide or immunoconjugate and an acidic variant thereof, such as a deamidated variant, using anion exchange chromatography. The present invention also provides compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.
