BEHENNA Douglas Carl,BEHENNA Douglas Carl,CHENG Hengmiao,CHENG Hengmiao,CHO-SCHULTZ Sujin,CHO-SCHULTZ Sujin,JOHNSON JR. Theodore Otto,JOHNSON JR. Theodore Otto,KATH John Charles,KATH John Charles,NAGA
申请号：
SI201430806
公开号：
SI3071570T1
申请日:
2014.11.10
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
