BEHENNA DOUGLAS CARL,CHENG HENGMIAO,CHO-SCHULTZ SUJIN,JOHNSON THEODORE OTTO JR,KATH JOHN CHARLES,NAGATA ASAKO,NAIR SAJIV KRISHNAN,PLANKEN SIMON PAUL
申请号：
AP2016009219
公开号：
AP2016009219A0
申请日:
2014.11.10
申请国别(地区):
AP
年份:
2016
代理人:
摘要：
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
