INTERFERON a2B VARIANTS

• 收藏
• 分享

专利权人:

发明人:

BEHRENS COLLETTE,DOYLE ANTHONY,CLARKE ADAM,POLLARD MATTHEW,DOMAGALA TERESA

申请号：

IN201717015133

公开号：

IN201717015133A

申请日:

2017.04.28

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention provides a fusion polypeptide comprising a first domain and a second domain wherein the first domain comprises a polypeptide ligand which binds to a cell surface associated antigen and the second domain comprises aglycosylated interferon a 2b (IFNa2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFNa2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFNa2b.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/