Josef Prassler;Marta Cortes-Cros;Adrian Walmsley;William Leonard Wishart;Ingo Klagge
发明人:
Adrian Walmsley,William Leonard Wishart,Marta Cortes-Cros,Josef Prassler,Ingo Klagge
申请号：
US13616226
公开号：
US20130071400A1
申请日:
2012.09.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule； an expression vector comprising said polynucleotide； an expression system comprising a polynucleotide capable of producing a binding molecule； an isolated host cell which comprises an expression system as defined above； the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity； a pharmaceutical composition comprising said binding molecule； and a method of treatment of diseases associated with axonal degeneration and demyelination.
