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IMMUNOCOMPETENT CELL AND EXPRESSION VECTOR EXPRESSING REGULATORY FACTORS OF IMMUNE FUNCTION
专利权人:
YAMAGUCHI UNIVERSITY
发明人:
TAMADA, Koji,SAKODA, Yukimi,ADACHI, Keishi
申请号:
SG11201807857P
公开号:
SG11201807857PA
申请日:
2017.03.15
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
It is to provide an immunocompetent cell that expresses regulatory factors of i mmunocompetent cell immune function and posses ses all of proliferative potential, viability, and the ability to accumulate a T cell, and an ex pression vector of regulatory factors of immune function for generating the immunocompetent cell. An immunocompetent cell expressing a cell surface molecule specifically recognizing a cancer antigen, interleukin 7 (IL-7), and CCL19 is generated. Preferably, the cell surface molecule specifically recognizing a cancer antigen is T cell rece ptor specifically re cognizing the cancer antigen, and the immunocompetent cell is a T cell.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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