INNOVATIVE CELLULAR THERAPEUTICS CO., LTD.;INNOVATIVE CELLULAR THERAPEUTICS INC.
发明人:
XIAO, LEI,PU, CHENGFEI,CAO, ZHIYUAN,WU, ZHAO,MAO, LI,BI, MAO
申请号：
CA3088161
公开号：
CA3088161A1
申请日:
2019.01.10
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to compositions and methods for enhancing T cell response and/or CAR cell expansion in vivo and/or in vitro. For example, a cell may comprise a first chimeric antigen receptor (CAR) and a second CAR, wherein a binding domain of the first CAR binds a first antigen, and a binding domain of the second CAR binds a second antigen. The first antigen is different from the second antigen. In embodiments, the first CAR may recognize a surface molecule of a blood cell.
