A sound enhancement system of an engine of a vehicle includes a vibration sensor disposed on the casing of the engine to generate an electrical signal indicative of the engine sound. A signal processor is connected to the vibration sensor to process the electrical signal-indicative of the engine sound and generate an output audio signal. A speaker is disposed in the vehicle compartment and connected to the signal processor to receive the output audio signal and generate an enhancement sound of the engine sound.Mevcut buluş, vajinal yoldan uygulanan lipoik asidin servikal kısalığa sahip gebe kadınlarda kürtaj ya da erken doğum tehdidinin tedavisine ve/veya önlenmesine yönelik kullanımıyla ilgilidir.