ENHANCING THE EFFECT OF CAR ENGINEERED T CELLS BY MEANS OF NUCLEIC ACID VACCINATION

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专利权人:

发明人:

SAHIN UGUR,REINHARD KATHARINA,SIMON PETRA,MROZ KAROLINA ANNA,HOBOHM KATHLEEN

申请号：

IN201747039720

公开号：

IN201747039720A

申请日:

2017.11.08

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

in vivoin vivoThe present invention generally embraces the treatment of diseases by targeting cells expressing an antigen on the cell surface. In particular the invention relates to a method for stimulating priming and/or expanding T cells genetically modified to express a chimeric antigen receptor (CAR) targeted to an antigen comprising contacting the T cells with the antigen or a variant thereof . In one embodiment the antigen or variant thereof is provided by administering a nucleic acid encoding the antigen or variant thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/