XIAO, Lei,PU, Chengfei,CAO, Zhizuan,WU, Zhao,MAO, Li,BI, Mao
申请号：
EP19700326
公开号：
EP3544618A4
申请日:
2019.01.10
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present disclosure relates to compositions and methods for enhancing T cell response and/or CAR cell expansionin vivoand/orin vitro.For example, a cell may comprise a first chimeric antigen receptor (CAR) and a second CAR, wherein a binding domain of the first CAR binds a first antigen, and a binding domain of the second CAR binds a second antigen. The first antigen is different from the second antigen. In embodiments, the first CAR may recognize a surface molecule of a blood cell.
