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Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one lactic acid salts
专利权人:
Novartis AG
发明人:
Harwood, Eric,Gullapalli, Rampurna,Ryckman, David,Shang, Xiao,Okhamafe, Augustus,Zhu, Shuguang,Chou, Joyce
申请号:
AU2006249847
公开号:
AU2006249847B2
申请日:
2006.05.23
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to non-hydrate crystalline forms of 4-amino- 5-fluoro-3 -[6-(4-methylpiperazin- 1 -yl)- 1 H-benzimidazol-2-yl] - 1 H-quinolin-2-one lactic acid salts, solid pharmaceutical formulations containing the same and methods of use. The present invention also relates to crystalline hydrates of 4-arnino-5-fiuoro-3-[6-(4- methylpiperazin-l-yl)-lH-benzimidazol-2-yl]-lH-quinolin-2-one lactic acid salts, pharmaceutical formulations containing the same and methods of use related thereto. The present invention further relates to crystalline solvates of 4-amino-5-fluoro-3-[6-(4- methylpiperazin-l-yl)-lH-benzimidazol-2-yl]-lH-quinolin-2-one lactic acid salts.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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