Composite Formulation of Dutasteride and Tadalafil Comprising Glycerol Fatty Acid Ester Derivative or Propylene Glycol Fatty Acid Ester Derivative and Oral Capsule Formulation Comprising the Same
Taegon Baik,Seyeon Kim,Ju-Hee Kim,Seung Han Song,Young-Joon Park
申请号：
US16099482
公开号：
US20190216827A1
申请日:
2017.05.12
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention is related to a composite formulation of dutasteride and tadalafil, therapeutic agents for prostatic hyperplasia, and to an oral capsule preparation containing the same. The composite formulation has the total amount of the composition inside a capsule of 400 mg or less so that the size of the capsule is convenient for the patient to take so as to increase patients' convenience, and includes a glycerol fatty acid ester derivative or a propylene glycol fatty acid ester derivative which may increase the solubility of dutasteride, a poorly soluble medicament and improve the stability of tadalafil so as to dissolve dutasteride and disperse tadalafil.
