This application discloses compounds derived from tetrahidroquinolina,Or a pharmaceutically acceptable Salt thereof has an Inhibitory activity against Colesteril ester transfer protein (CETP).Claim 1: a compound that is characterized by the formula (1), where r u00b9 is a hydrogen Atom, an optionally substituted Group alcoxicarbonilo,A Group carbamoilo optionally substituted alkyl group, an optionally substituted, a group alcanoilo optionally replaced,A monocyclic or bicyclic Heterocyclic Group containing saturated or unsaturated 1-4 heteroatoms selected from Oxygen independently,Sulphur and Nitrogen Atoms (the group is optionally substituted Heterocyclic)Carbonyl group or a monocyclic or bicyclic Heterocyclic saturated or unsaturated containing 1 to 4 heteroatoms selected from Oxygen Atoms independently.Sulphur and Nitrogen (optionally substituted Heterocyclic Group； R u00b2) is a hydrogen Atom or an optionally substituted alkyl group； r u00b3 is a hydrogen Atom or an alkyl group opcionalmBeing replaced； r u2074 is a group alquileno optionally substituted； r u2075 is a monocyclic or bicyclic Heterocyclic Group containing saturated or unsaturated heteroatoms independently Select 1 to 4A of Atoms of Oxygen, Sulfur and Nitrogen, where the group is replaced by 1 to 5 Heterocyclic substituents selected from the following groups.Or the group is substituted by Heterocyclic substituents selected from groups 1 to 5 below and in addition a Halogen Atom, hydroxyl Group and / or an oxo Group, cyano, Nitro Group,Carboxy Group, sulfo Group, alkyl group c u2083 u208b u2081 u2080 Group substituted alkyl, cycloalkyl, optionally substituted Group, Group alquenilo optionally substituted alkoxyl Group c u2083 u208b u2081 u2080,Group Group cicloalcoxilo alkoxyl substituted, optionally substituted, optionally substituted alcoxicarbonilo Group, Group carbamoilo optionally replaced,Carbamimidoilo Group optionally substituted, optionally substituted Alquiltio Group, Group alquilsulfinilo
