The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin;Solvotrin Therapeutics Ltd.
发明人:
申请号：
EP12701715.0
公开号：
EP2665730A1
申请日:
2012.01.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C1-C8 alkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, which can be unsubstituted or substituted with at least one nitric oxide releasing group； and/or at least one of hydroxide, -Cl, -Br, a C1-C8 alkyl, benzyl, a C1-C8 alkoxy, benzyloxy, -NHC(O)R, -NH2, -NO2-ONO2, -(CH2)nONO2, -OC(O)[(CH2)n]cyclicONO2, -OCOArONO2, -OCOAr(CH2)nONO2 or a C1-C5 haloalkyl ester, wherein R is a C1-C8 alkyl or a C1-C8 alkoxy group, n=1-8 and m=3-10, to produce a super-aspirin effect.
