The present invention discloses novel compounds and their use in medicine. Preferably the compounds are applicable in the therapy of disorders associated with damaged post-mitotic tissues in mammals.The novel compounds are compounds according to formula Iwherein- X is O (oxygen) or S (sulphur),- R1 is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted alkyl groups, cycloalkyl groups, alkylcycloalkyl groups, aryl groups, alkylaryl groups, arylalkyl groups, cycloalkylaryl groups and arylcycloalkyl groups, which optionally contain heteroatoms,- R2 is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted C1 - C6 alkyl groups, C1 - C6 alkoxy groups, C1 - C6 alkoxy alkyl groups and C2 - C6 alkenyl groups,- R3 is is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted alkyl groups, cycloalkyl groups, alkylcycloalkyl groups, aryl groups, alkylaryl groups, arylalkyl groups, cycloalkylaryl groups and arylcycloalkyl groups, which optionally contain heteroatoms,- or a stereoisomer, a tautomer, a prodrug or a pharmaceutically acceptable salt thereof.