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Novel compounds for regeneration of terminally-differentiated cells and tissues
专利权人:
Acousia Therapeutics GmbH
发明人:
Bos, Michael
申请号:
AU2014350358
公开号:
AU2014350358A1
申请日:
2014.11.06
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention discloses novel compounds and their use in medicine. Preferably the compounds are applicable in the therapy of disorders associated with damaged post-mitotic tissues in mammals. The novel compounds are compounds according to formula I (I) wherein - X is O (oxygen) or S (sulphur), - R1 is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted alkyl groups, cycloalkyl groups, alkylcycloalkyl groups, aryl groups, alkylaryl groups, arylalkyl groups, cycloalkylaryl groups and arylcycloalkyl groups, which optionally contain heteroatoms, - R2 is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted C1 - C6 alkyl groups, C1 – C6 alkoxy groups, C1 – C6 alkoxy alkyl groups and C2 – C6 alkenyl groups, - R3 is a substituent selected from the group consisting of straight-chain (unbranched) or branched, unsubstituted or substituted alkyl groups, cycloalkyl groups, alkylcycloalkyl groups, aryl groups, alkylaryl groups, arylalkyl groups, cycloalkylaryl groups and arylcycloalkyl groups, which optionally contain heteroatoms, - or a stereoisomer, a tautomer, a prodrug or a pharmaceutically acceptable salt thereof.
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