TAKADA KENZO,TAKADA Kenzo,NAKAJIMA KANTOU,NAKAJIMA Kantou,KISTLER BARBARA,KISTLER Barbara,PARK JOHN,PARK John
申请号:
SI200830911
公开号:
SI2215119T1
申请日:
2008.11.12
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.