Takada, Kenzo,Nakajima, Kantou,Kistler, Barbara,Park, John
申请号:
AU2013203909
公开号:
AU2013203909A8
申请日:
2013.04.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013203909A820130627.pdf#####H:\1CMenvoven\NR0orMUC\SCUGU63643_l.iJUU-lU/U4/2013 ABSTRACT Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. 5 Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.