TAKADA, KENZO,NAKAJIMA, KANTOU,KISTLER, BARBARA,PARK, JOHN
申请号:
DK08848696
公开号:
DK2215119T3
申请日:
2008.11.12
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.