John Park;Barbara Kistler;Kenzo Takada;Kantou Nakajima
发明人:
Kenzo Takada,Kantou Nakajima,Barbara Kistler,John Park
申请号：
US12681396
公开号：
US08679502B2
申请日:
2008.11.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.
