Biodegradable copolymer hydrogel materials are provided. The biodegradable copolymer hydrogel material has a structure of formula (I) or formula (II) AB-BOX-BA BAB-(BOX-BAB)n-BOX-BAB formula(I) formula(II) wherein, A comprises a hydrophilic polyethylene glycol polymer; B comprises a hydrophobic polyester polymer; BOX is bifunctional group monomer of 2, 2'-Bis(2-oxazoline) and used for coupling the blocks AB or BAB; and n is an integer and the same or more than 0.本發明提供一生物可分解共聚合物水膠材料。該生物可分解共聚合物水膠材料符合下列公式(I)或(II)所示結構:;AB-BOX-BA BAB-(BOX-BAB)n-BOX-BAB;公式(I) 公式(II);其中,A嵌段高分子係為一親水性聚乙二醇聚合物(hydrophilic polyethylene glycol polymer);B嵌段高分子係為一疏水性聚酯聚合物(hydrophobic polyester polymer);BOX係為2,2'-雙(2-噁唑啉)(2,2'-Bis(2-oxazoline))之雙官能基單體,用以交聯雙團聯AB;以及,n係為一整數,且n>=0。