Johannes Backs,Zegeye Jebessa,Lorenz Lehmann,Hugo Katus,Oliver Müller
申请号：
US15881935
公开号：
US20180258407A1
申请日:
2018.01.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to Abhydrolase containing domain 5 (ABHDS) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHDS for the identification of novel compounds which are useful for the treatment of heart failure.
