Johannes Backs,Zegeye Jebessa,Lorenz Lehmann,Hugo Katus,Oliver Müller
申请号：
US14768050
公开号：
US20160108376A1
申请日:
2014.02.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
