FRAGMENTS ET VARIANTES PARTIELLES DE HDAC4 COMME APPROCHE THÉRAPEUTIQUE POUR LE TRAITEMENT DE MALADIES CARDIOVASCULAIRES

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专利权人:

Ruprecht-Karls-Universität Heidelberg

发明人:

申请号：

EP19174484.6

公开号：

EP3597213A1

申请日:

2014.02.17

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.

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中国工程科技知识中心

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