A medical device for collecting cells includes a delivery tube having a flexible wire disposed within a lumen of the tube. The flexible wire includes a rigid proximal portion and a flexible distal portion. The flexible distal portion includes a cell collecting portion that can be advanced out of the needle and into a body cavity. The flexible nature of the wire will allow it to generally fill the body cavity to increase the contacted surface area and the amount of cells that are collected. The wire can then be retracted back into the needle for removal from the patient's body.