Smith II, Leon M.,Ladziata, Vladimir,Delucca, Indawati,Pinto, Donald J. P.,Orwat, Michael J.,Dilger, Andrew K.,Pabbisetty, Kumar Balashanmuga,Yang, Wu,Shaw, Scott A.,Glunz, Peter W.,Panda, Manoranjan
申请号:
AU2017206820
公开号:
AU2017206820A1
申请日:
2017.01.13
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.