LADZIATA, VLADIMIR,GLUNZ, PETER W.,HU, ZILUN,WANG, YUFENG
申请号:
SG11201700251P
公开号:
SG11201700251PA
申请日:
2015.07.14
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.