TORA George O.;TANGIRALA Raghuram;BRISTOL-MYERS SQUIBB COMPANY;GLUNZ Peter W.;MAISHAL Tarun Kumar;THIYAGARAJAN Kamalraj;DE LUCCA Indawati;LADZIATA Vladimir
发明人:
TORA George O.,LADZIATA Vladimir,GLUNZ Peter W.,DE LUCCA Indawati,MAISHAL Tarun Kumar,TANGIRALA Raghuram,THIYAGARAJAN Kamalraj
申请号:
IL27190520
公开号:
IL271905D0
申请日:
2020.01.08
申请国别(地区):
IL
年份:
2020
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.