GLUNZ, Peter W.,HU, Zilun,LADZIATA, Vladimir,WANG, Yufeng
申请号:
TN2017000009
公开号:
TN2017000009A1
申请日:
2015.07.14
申请国别(地区):
TN
年份:
2018
代理人:
摘要:
The present invention provides compounds of Formula (1): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologie,neuropathologie, autoimmune, fibrotic, and/or inflammatory disorders using the same.