Leon M. Smith, II,Vladimir Ladziata,Indawati De Lucca,Donald J.P. Pinto,Michael J. Orwat,Andrew K. Dilger,Kumar Balashnmuga Pabbisetty,Wu Yang,Scott A. Shaw,Peter W. Glunz,Manoranjan Panda
申请号：
US16739363
公开号：
US20200131200A1
申请日:
2020.01.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides compounds of Formula (I):or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
