Xiao, Dengming,Zhu, Li,Hu, Yuandong,Wang, Shixin,Yu, Rong,Hu, Wei,Liang, Zhi,Liu, Xijie,Hu, Quan
申请号：
AU2011325657
公开号：
AU2011325657A1
申请日:
2011.11.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly- morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
