NOVEL 6-ARYLAMINO PYRIDONE CARBOXAMIDE AS MEK INHIBITORS

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专利权人:

发明人:

申请号：

EP11837567.4

公开号：

EP2635587A1

申请日:

2011.11.01

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly-morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.

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中国工程科技知识中心

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http://www.ckcest.cn/home/