CENTAURUS BIOPHARMA CO., LTD.;CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
发明人:
XIAO, DENGMING,ZHU, LI,HU, YUANDONG,WANG, SHIXIN,YU, RONG,HU, WEI,LIANG, ZHI,LIU, XIJIE,HU, QUAN
申请号：
CA2829117
公开号：
CA2829117A1
申请日:
2011.11.01
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly- morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
